I did my BSc in Experimental Medicine in Peking University Health Science Centre in Beijing, where I became interested in all the techniques used in biochemistry and molecular biology. After graduation, I joined Prof. Andrew Sharrocks’ lab at the University of Manchester as a PhD student, studying the DNA binding specificity of different Forkhead transcription factors. During this period, I discovered an evolutionarily conserved transcription factor complex that regulates G2/M cell cycle transition.
After my PhD, I joined Dr. Sarah Teichmann’s group at the EBI as a postdoc to investiage T helper cell 2 (Th2) differentiation from an epigenetic point of view. In 2016, the Teichmann lab moved to the Sanger Institute, and I became a Senior Staff Scientist in the lab. During that period, I was mainly working on techniques to interrogate the gene expression and epigentic profiles at the single cell level. I developed a simple and robust way of performing scATAC-seq so that everybody can easily investigate chromatin accessibility at the single cell level.
In 2019, I joined the Department of Biology in SUSTech, Shenzhen, China as an Assistant Professor. My lab study transcriptional regulation in cell fate decision and memory. My lab website is coming soon … hopefully …
About this website
I write stuff here to explain things that I’m trying to understand for my own education. The theme for this website is forked from beautiful-jekyll by Dean Attali. If you are into genomics data, you will be very familiar with the favicon of this website. It is a genome coverage track screenshot taken from a scATAC-seq data from one of my experiments.
Some random thoughts about myself:
I have a typical Chinese name (Xi Chen, 陈曦).
I like certain types of music, including folk, gothic metal, death metal, melodic death metal, power metal, progressive metal. Most of my favourite bands are from Finland, Sweden and Norway.
I play one computer game: Diablo II. I’ve been playing this game over and over again for years, and I have found the rarest item in the entire game (Tyrael’s Might).
I also play some 8-bit NES games: the Ninja Gaiden triology, Megaman 1 and 2, Castlevania.